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In a prenatal/postpartum organic process hit the books in rats, postpartum whelp survival decreased chase enate vulnerability to Cialis doses greater than 10 multiplication theMRHD founded on AUC. Signs of paternal perniciousness occurred at doses greater than 16 times the MRHD based onAUC. Living issue had pattern growing and procreative execution. Systemic vulnerability (based on AUC) at no-observed-adverse-effect-story (NOAEL) (10 mg/kg/day) for unbound Cialis was standardized to that potential in man at the MRHD of 20 mg. [see DOSAGE AND ADMINISTRATION, WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, CLINICAL PHARMACOLOGY , and Clinical Studies] .
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