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The consequences of GM2 ganglioside accruement are far-reaching, affecting the maturation and social occasion of versatile parts of the nervous system. It disrupts the rule growth and ontogeny of the brain, starring to terrible developmental delays. The accretion of GM2 ganglioside is a tacit but unrelenting enemy, steadily eroding the anxious organisation and finally in the lead to the devastating neurologic declension seen in Tay-Sachs disease.
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