Polynucleotides

Unlocking Radiant Skin.

of nucleotide monomers. They are essentially long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules have roles in the body, including repair and . In aesthetic treatments, polynucleotides are used for their properties, helping to skin by promoting cell and healing.

This treatment helps to stimulate regenerative processes, to improved skin texture, elasticity, and hydration.

It is also great for people who want to prevent the signs of ageing on the skin.

What are Polynucleotides?

Polynucleotides are long chains of nucleotides, which are the blocks of DNA and RNA. These molecules are from salmon DNA, which has been found to be highly with human tissue.

The treatment works at a cellular level to tissue repair, promote collagen production, and skin quality.

Key benefits of Polynucleotides

Polynucleotides offer advantages for skin health and appearance:

skin and tone

in fine lines and wrinkles

Enhanced skin and elasticity

Brighter, more radiant complexion

in pigmentation and dark (particularly around the eyes)

appearance of scars and stretch marks

Overall skin rejuvenation

Polynucleotides Packages:

Per area: £350

Per area: £600

Per area: £850

FAQs

At Karwal Aesthetics, we offer Plinest for various areas of the face and body:

Face: Mid-face and lower face

Eyes: Under-eye area, crow’s feet, upper eyelids

Neck and décolletage: For addressing crepey skin and lines

Hands: To improve skin and reduce visible signs of ageing

The number of treatments required varies depending on individual and goals:

Initial course: 2-4 sessions spaced 2-4 weeks apart

Maintenance: every 6 months to results

Severe concerns: May more treatment protocols

Results from polynucleotide develop gradually:

Immediate: Some hydration and subtle glow may be away

2-4 weeks: in skin and tone

4-8 weeks: More significant improvements as collagen production increases

3-6 months: Optimal results become apparent

typically last 6-12 months, depending on such as age, lifestyle, and skin .

are suitable for most adults looking to improve their skin . Ideal candidates include those who:

Have early to moderate signs of ageing

Want rejuvenation without fillers

Have sun-damaged or dehydrated skin

Are for preventative anti-ageing treatments

Have about results

We offer polynucleotide treatments at our clinic in London Mayfair. Our is located in the heart of Mayfair, one of London’s most prestigious areas, making it easily for clients across the capital.

Clinic Location

Address: 15 Dover Street, London, W1S 4LP

Our Mayfair clinic provides a luxurious and discreet environment where you can receive your Plinest treatments from Dr Arun, an aesthetic . The clinic is equipped with modern and adheres to the of safety and hygiene.

How to Find Us

By Underground: Green Park (Jubilee, Piccadilly, and Victoria lines) is just a short walk away

By Bus: Multiple bus routes serve the Mayfair area

By Car: street available; car parks nearby

To book your polynucleotides or treatment, .

Improved Skin Texture: The treatment helps to smooth out fine lines and wrinkles, giving the skin a more refined texture.

Enhanced Elasticity: By collagen production, Plinest Eyes skin elasticity, making it more resilient and firm.

Hydration: The polynucleotides help to levels in the skin, and dullness.

Natural-Looking Results: The regenerative of provide a subtle and enhancement, the overly look that some can .

Minimal Downtime: Plinest Eyes is a invasive with little to no downtime, individuals to resume their daily activities shortly after treatment.

Aftercare Notes for Sunekos, Profhilo & Plinest:

Needle entry points, redness, bruising, and asymmetry around sites immediately after is normal due to the very nature of the .

There may also be some tenderness present as the bruising and inflammation sets in. These symptoms will resolve over the next 2-7 days, on your individual to the .

For 24 hours avoid:

your face

makeup

Skincare with active ingredients

No alcohol

No exercise

No hot showers or sauna/steam rooms

Both and Sunekos are bio-revitalisation treatments, but they differ in their composition and of action. a formula of hyaluronic acid combined with a blend of amino acids, whilst Plinest uses derived from salmon DNA.

Key differences include:

Active ingredients: relies on acid and amino acids to stimulate the extracellular matrix, whereas Plinest uses polynucleotides for cellular and tissue repair.

Mechanism: Sunekos works by providing the building blocks for collagen and synthesis, whilst actively fibroblast activity and has anti-inflammatory and antioxidant .

Treatment areas: Both can be used on similar areas, though Plinest Eye is specifically formulated for the periorbital region, whilst Sunekos has different formulations (Sunekos 200 and Sunekos 1200) for levels of skin laxity.

Results: Both natural-looking improvements. However, Sunekos is the preferred at Karwal Aesthetics, more dramatic results and better in hyperpigmentation, fine lines, and skin texture—especially crepey skin.

Both and Profhilo are bio-remodelling that stimulate skin rejuvenation, but they differ in their and approach:

Active ingredients: contains highly concentrated acid (HA), whilst uses polynucleotides derived from salmon DNA.

Mechanism of action: works through bio-remodelling with HA to stimulate collagen and elastin production in four different types of . works by directly stimulating fibroblast activity and has additional anti-inflammatory and properties.

technique: typically uses the BAP (Bio Aesthetic Points) with 5 points per side of the face, whilst Plinest requires injection points distributed across the treatment area.

Spread: unique formulation allows it to spread more easily under the skin after injection, whilst Plinest remains more localised to the injection sites.

Hydration vs. regeneration: Profhilo primarily focuses on intense hydration and bio-remodelling, whilst cellular regeneration, tissue repair, and anti-inflammatory .

areas: Both can be used on similar areas, though is particularly noted for its and hydrating effects on the face and neck, whilst offers formulations like Plinest Eye for concerns.

Results: Both natural-looking . However, Profhilo is the preferred product at Karwal Aesthetics between the two. delivers a glow, plumpness, and hydration to the skin.

Plinest Polynucleotide – https://Www.tlcark.com/, are generally well-tolerated, but some side may occur:

Mild at injection sites

Slight bruising (more common in sensitive areas)

Redness or tenderness

Small bumps at injection points

These effects resolve within hours. Serious side are rare when performed by qualified practitioners.

Enquiries

Mayfair, London2nd Floor, 15 Dover Street, W1S 4LP

Closed

10: :00

Select Dates

Closed

Monday

Tuesday

Wednesday

Thursday

Friday

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Sunday

0% finance is available on all treatments from £500. Find out more by visiting our Payment Plan page.

Please note: our clinic is on the second floor with stair access only.

plinest